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SPECT is a functional imaging technique that is mainly used for studies of regional cerebral blood ow (rCBF). SPECT studies in adults with eating disorders have been inconclusive. Krieg et al. (1989) reported no change in regional blood ow in patients with anorexia nervosa before and after eating or when compared with a control group. Nozoe et al. (1993) reported an increase in rCBF in response to food intake in the left inferior frontal cortex in patients with anorexia nervosa. Gordon et al. (1997) showed unilateral temporal lobe hypoperfusion in 13 out of 15 children and adolescent patients with anorexia nervosa. The authors speculate as to whether this is a primary nding since temporal lobe hypoperfusion persisted in three patients who had regained normal weight. Furthermore, changes in the brain secondary to starvation would be expected to produce global and symmetrical changes. SPECT can also be used to study neurotransmitter systems. In addition to those compounds used for measuring blood ow, iodine labeled ligands for the muscarinic, dopaminergic, and serotonergic receptors can be used. [123 ]Beta-CIT SPECT studies are used to investigate the availability of brain serotonin transporters (SERT) and dopamine transporters (DAT). Tauscher et al. (2000) performed scans in 10 medication-free, bulimic patients and 10 age-matched controls. They found a 17% reduced SERT availability in hypothalamus and thalamus and a similar reduction in striatal DAT availability. In addition, there was a negative correlation between illness duration and SERT availability. As with other alterations it remains unclear whether reduced SERT availability might be an etiologic defect, adaptive mechanism or an unrelated epiphenomenon of another etiologic lesion.

In data analysis, it is important to discover dependencies between the condition and decision attributes. Using these dependencies, one can identify and omit the unnecessary attributes (which are considered to be redundant information in the decision system) and the corresponding values for making decision or classi cation. Intuitively, we say that a set of decision attributes Td depends totally on a set of condition attributes Tc, denoted as Tc ) Td, if all the values of decision attributes are determined uniquely by values of the condition attributes. This implies that there exists a functional dependency between values of Tc and Td. Note that the dependency can also be partial, which means that only some values of Td can be determined by values of Tc. Now we give its formal de nition: De nition D.7. Let C and D be subsets of A, D \ C 6 ; and D [ C A. We say that D depends on C in a degree k 0 k 1 , denoted C )k D, if k g C; D X jCXj jUj X2U=D D:11

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IBM PC IBM dominated the large-scale computer industry in 1970, holding more than 70% of the market. IBM had several advantages. First, it had a nationwide sales force already serving most businesses looking to buy computers. Second, it already understood how to automate recordkeeping. Third, IBM leased instead of sold its equipment. Long after the machinery had paid for itself, lease checks kept rolling in. Things were about to change, however, in 1972, with Intel Corporation s introduction of the 8008, the rst 8-bit microprocessor. But, as always, software had to catch up with the new hardware before major advances could be achieved. Bill Gates, Paul Allen, Gary Kildall, and others were players in the software development events leading to the introduction and remarkable success of the IBM PC. With the popularization of personal computing in 1975, Paul Allen and Bill Gates seized the opportunity on the software front and developed BASIC for the Altair 8800. This quiet event resulted in the birth of Microsoft, an event that would have major and long-lasting implications for the personal computer industry. Microsoft was created when Gates and Allen, childhood friends,

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