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Change Your In-Hospital Medical Cost Coverage Issue: Response: A large government agency in Texas sought to keep its health and prescription drug costs down. The agency changed to a three-tiered prescription program and reduced its hospital in-network coverage from 100% to 90%, its chief of benefits development and administration said. The medical cost trend was reduced 5.4% ($93 per member), and pharmacy claims per utilizing member decreased 2.7% ($12).

Application to Learning Graphical Models As an illustration of how guided random search can be used to learn graphical models from data, we consider a simulated annealing approach to learning undirected graphs with hypertree structure28 [Borgelt and Gebhardt 1997] That is, we consider a method that tries to find a family of sets of attributes having the running intersection property, so that the corresponding undirected graph (that is, the undirected graph, the maximal cliques of which are induced by these attribute sets) is optimal wrt a given evaluation measure Trying to find directly the maximal cliques of an undirected graph instead of working with individual (directed or undirected) edges has several advantages: in the first place, compared to an approach based on directed acyclic conditional independence graphs the larger search space is avoided (cf Section 731).

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Secondly, compared to an approach based on arbitrary undirected conditional independence graphs we need not determine the maximal cliques of graphs which is necessary for evaluating them, because we have to compute the factor potentials on the maximal cliques (cf Sections 333, 422, and 52) or an equivalent thereof but have them readily available In addition, for an undirected graph with hypertree structure it is much simpler to.

of objects, the invocation of the requested operation and the synchronization of client and server Transport layer implementations, such as TC P and U DP, use addressing schemes based on host names and port numbers Remote procedure call systems use the p o r t m a p daemon in order to map between service names and host names To achieve this mapping, service names defined by system administrators have to be unique Object-oriented middleware extends the basic idea of portmaps in several respects First, addressing of server objects is based on object references Secondly, these object references are generated by the middleware rather than an administrator Finally, the session layer implementation of objectoriented middleware maps object references to hosts in a fully transparent way Client objects always identify the object from which they request the service by an object reference.

where is the half angle of the cone of specimen light accepted by the objective lens and n is the refractive index of the medium between the lens and the specimen. For dry lenses used in air, n 1; for oil immersion objectives, n 1.515. The diffraction angles capable of being accepted by dry and oil immersion objective lenses are compared in Figure 6-2. By increasing the refractive index of the medium between the lens and coverslip, the angle of diffracted rays collected by the objective is increased. Because immersion oil has the same refractive index as the glass coverslip

S S To simplify the notation, let A = Fk 2 :S1 and B = Fk 1 :S1 . The maximum relative error performed by the algorithm on either input S2 : S1 or input S1 : S1 is

On the whole, peripheral energy balance and satiety signals appear to function normally given the state of under-nutrition in acute AN However, enhanced CCK satiety signalling and elevated central leptin concentrations might play a role in maintenance of the disorder, while elevated leptin for BMI during rapid refeeding may contribute to dif culty restoring weight Subtle abnormalities of the insulin and cortisol response to a meal following recovery could re ect residual damage to gastrointestinal function, or a vulnerability factor for the disorder Imbalance between the orexigenic and anorexigenic pathways of the hypothalamus may therefore be implicated in the appetite disturbance of AN An aberrant HPA axis response to chronic stress, characterised by persistently elevated CRH activity, may be one factor that contributes to the pathophysiology of AN However, it is likely that other neuropeptide and neurotransmitter systems also play an important role.

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