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metabolite depletion Phosphagens (ATP and PC) Adenosine triphosphate (ATP) is the major energy source for cross-bridge cycling and the ionic pumps such as sarcoplasmic reticulum (SR) Ca2+ pump and the surface membrane sodium pump (Allen et al 1992) The breakdown of ATP to adenosine diphosphate (ADP) and the rephosphorylation of ADP back to ATP form the ATP ADP cycle Phosphocreatine (PCr) is the immediate source of ATP rephosphorylation (Brooks et al 1996) The available quantities of both ATP and PCr are relatively small (27 and 90 mmol kg 1 dry weight ATP and PCr for fast-twitch muscles, respectively, and 19 and 58 mmol kg 1 dry weight ATP and PCr, respectively, for slow-twitch bers (Fitts 1994)) Thus, one of the classic theories of peripheral fatigue suggests that depletion of ATP and PCr contributes to fatigue during exercise.

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Note The variable $number in the preceding code is converted to a string implicitly within both the substring() and string length() functions. Alternatively, you can use the remainder after dividing the number by 10:

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While a number of studies have found strong correlations between ATP and PCr concentrations at fatigue, debate exists as to whether this is causative or simply a consequence of muscle contraction (Roberts & Smith 1989) The majority of evidence suggests that cell ATP concentrations do not decline to a critical level that would impair contraction, with numerous studies reporting levels rarely declining more than 60 70% of pre-exercise.

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1 Raj Bawa, Nanotechnology Patenting In The US, 1 Nanotech L&B 31 (2004) 2 US Const, art I, 8, cl 8 3 Fritz Machlup identified four different positions on which advocates of patent protection have rested their case: (1) the natural law thesis; (2) the rewardby-monopoly thesis; (3) the monopoly-profit-incentive thesis; and (4) the exchange for secrets thesis Fritz Machlup, An Economic Review of the Patent System, Study No 15 of the Subcomm on Patents, Trademarks, and Copyrights of the Committee on the Judiciary United States Sen, 85th Cong 21 (1958) The natural-law thesis holds that people have natural property rights in their own ideas Society is morally obligated to recognize and protect this property right Id The reward-by-monopoly thesis maintains that justice requires that people receive reward for their services in proportion to their usefulness to society Id.

The monopoly-profit-incentive thesis assumes that inventions and/or their exploitation will not be obtained in sufficient measure if inventors and capitalists can hope only for such profits as the competitive exploitation of all technical knowledge will permit Id Finally, the exchange for secrets thesis portrays the issuance of a patent as a bargain between inventor and society Id The inventor surrenders the possession of secrecy knowledge in exchange for the protection of a temporary exclusivity in its industrial use Id Machlup concluded that none of the theories justifies the existence of the patent system [I]f we did not have a patent system, it would be irresponsible, on the basis of our present knowledge of its economic consequences, to recommend instituting one But since we have had a patent system for a long time, it would be irresponsible, on the basis of our present knowledge, to recommend abolishing it Id at 80.

To my knowledge, only two companies offer VoIP cellular service. The first is the aforementioned BT Group, which offers service in Great Britain. It utilizes a home service plan and for the price of roughly U.S. $120 you get a phone, modem, and a calling plan. BT s phones use UMA. The other company offering this is Truphone, a company offering a beta test of the SIP for the Nokia E-Series phones, with downloads coming soon for the N-Series (N80, N91, N92, and N93) and Windows Mobile compatible phones. The technology isn t going to be limited for long, though. Phillips Semiconductors is manufacturing UMA chips for cell phones, Texas Instruments is coming out with WiLink 4.0, Ericsson is manufacturing UMA phones, and Qualcomm, Nortel, Verizon, and Sprint are all using a protocol called EV-DO Revision A. Motorola,

Almost without exception, services firms must rely on a variety of vendors to accomplish their objectives Outside vendors provide many of the functions outlined in this book, including legal, banking, information technology, telecommunications, marketing, public relations, and real estate services, as well as more mundane items such as office supplies, catering, and facilities Because professional services providers such as lawyers, consultants, real estate agents, or doctors get little training in managing outside partners, including experience measuring service levels, selecting service providers, and negotiating pricing and terms, many professional services firms fall short in vendor management This can be highly damaging to the firm, not only because of the reliance on vendors for such a wide variety of functions, but also because of the high expenditures on outside vendors In aggregate, outside providers generally comprise the largest expenditure of a professional services firm besides labor costs.

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