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9. Given the same information as in problem 5, diagram one of the possible meioses. How many different gametes can arise, absent crossing over What variation in gamete genotype is introduced by a crossover between the A locus and its centromere 10. How many bivalents, tetrads, and dyads would you nd during meiosis in human beings in fruit ies in the other species of table 3.3 11. Can you devise a method of chromosome partitioning during gamete formation that would not involve synapsis that is, can you reengineer meiosis without passing through a synapsis stage 12. What are the differences between a reductional and an equational division What do these terms refer to 13. How does the process of meiosis explain Mendel s two rules of inheritance 14. Drosophila has four pairs of chromosomes. Let chromosomes from the male parent be A, B, C, and D, and

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those from the female parent be A , B , C , and D . What fraction of the gametes from an AA BB CC DD individual will be a. all of paternal origin b. all of maternal origin c. half of maternal origin and half of paternal origin 15. Wheat has 2n 42 and rye has 2n 14 chromosomes. Explain why a wheat-rye hybrid is usually sterile. 16. The arctic fox has fty small chromosomes, and the red fox has thirty-eight larger chromosomes. Hybrids of these two species are sterile, but cytological studies during meiosis in these hybrids reveal both paired and unpaired chromosomes. a. Account for the sterility of the hybrids. b. How can you explain the paired chromosomes 17. An organism has six pairs of chromosomes. In the absence of crossing over, how many different chromosomal combinations are possible in the gametes

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for a wider range of materials [1] The choice of the material will depend on the matching of the properties of the material with the intended application As MEMS mainly deals with thin-film materials, the properties of the thin-film materials should be considered as they may differ from the properties of the bulk material The substrate in a microsystem is a flat macroscopic object on which microfabrication processes take place It also serves as a signal transducer besides supporting other transducers that convert mechanical actions to electrical outputs In semiconductors, the substrate is a single crystal cut into slices from a larger piece known as a wafer which originates from an ingot (Figure 830) [6] However, microsystems can be made of either active substrate materials or passive substrate materials Active substrate materials are primarily used for sensors and actuators Fig 830: A silicon wafer [4] in microsystems and other MEMS components Typical substrate materials used are silicon (Si), germanium (Ge), gallium arsenide (GaAs), quartz, glasses, metals, ceramics and polymers [4] As most of the materials are semiconductors, they can function either as a conductor or an insulator when the need arises Basically, these substrate materials have a cubic crystal lattice with a tetrahedral atomic bond which gives dimensional stability and is relatively insensitive to the environment [16] Of the various substrate materials, silicon is the most dominant material as it is possible to integrate circuits with MEMS devices The single-crystal silicon is generally used because it is widely available In addition, it is mechanically stable and serves as an ideal lightweight structural material Furthermore, as it has a melting point of 1,400 C, silicon is dimensionally stable even at elevated temperatures Silicon also has a low thermal expansion coefficient With virtually no mechanical hysteresis, it is suitable for use in sensors and actuators Silicon also allows a greater flexibility in the designing and manufacturing process [6] Silicon compounds such as silicon dioxide (SiO2), silicon carbide (SiC) and silicon nitride (Si3N4) are also used in making MEMS and microsystems In polycrystalline form, silicon can also be deposited onto silicon substrates by low pressure chemical vapour deposition (CVD) technology which is suitable for surface micromachining Piezoelectric crystals are one of the most common non-semiconducting materials Generally, piezoelectric crystals are solid ceramics, and they are capable of converting mechanical energy into electronic signals and vice versa Polymers which include plastics, adhesives, Plexiglas and Lucite are also used in the manufacture of MEMS and microsystems Polymers are made up of long chains of organic molecules which are mainly composed of hydrocarbons Photoresist polymers are used to produce masks for.

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